Radiator Fluid (Ethylene Glycol) Overdose
Description
Ethylene glycol is a solvent found in products ranging from antifreeze fluid and de-icing solutions to carpet and fabric cleaners. Ingestion causes transformation of the ethylene glycol into toxic byproducts that damage the kidneys and brain. If untreated the disorder can be fatal. Ingestions can be accidental or intentional.
Symptoms
Confusion, ataxia, hallucinations, slurred speech, coma, vomiting, hyperventilation, seizures, breathing problems, heart failure.
Tests
A history and physical exam will be performed. The diagnosis is made based on the history and the initial testing of the body's blood chemistry. An ethylene glycol level can be measured is usually not readily available to be clinically useful in the initial treatment.
- CBC
- Chem 12
- UA
- EKG
- BHCG
Treatment
Intravenous fluids and support of the cardiorespiratory status of the patient is essential. Seizures are treated with benzodiazepines. Fomepizole is administered to decrease the conversion of ethylene glycol into toxic metaboloites. Kidney dialysis is performed to correct severe metabolic derangements, remove the toxic metabolites and the ethylene glycol. For more information and help call your local poison center at 1-800-222-1222.
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