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Quaternary Syphilis (End Stage Syphylis)

Description

Description

An advanced form of syphilis. Syphilis is caused by the bacteria Treponema pallidum. Quatennarry syphilis is a progressive and advanced brain infection (encephalitis). Patients exhibit severe personality changes, unsteady gait, visual problems and seizures.

Symptoms

Symptoms

Personality changes, unsteady gait, incoordination, seizures, weakness, confusion, headaches, visual loss.

Tests

Tests

A history and physical exam will be performed. A CT scan and/or MRI is done to rule our other causes of the symptoms. A lumbar puncture is done to evaluate the CSF (cerebrospinal fluid), and detect the bacteria through antibody markers (RPR, VDRL).

Standard Workup
  • CBC
  • Chem 12
  • CT Scan
  • MRI
Treatment

Treatment

High dose penicillin is the treatment of choice.





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