Quaternary Syphilis (End Stage Syphylis)

Description
An advanced form of syphilis. Syphilis is caused by the bacteria Treponema pallidum. Quatennarry syphilis is a progressive and advanced brain infection (encephalitis). Patients exhibit severe personality changes, unsteady gait, visual problems and seizures.

Symptoms
Personality changes, unsteady gait, incoordination, seizures, weakness, confusion, headaches, visual loss.

Tests
A history and physical exam will be performed. A CT scan and/or MRI is done to rule our other causes of the symptoms. A lumbar puncture is done to evaluate the CSF (cerebrospinal fluid), and detect the bacteria through antibody markers (RPR, VDRL).
Standard Workup
- CBC
- Chem 12
- CT Scan
- MRI
Treatment
High dose penicillin is the treatment of choice.

Research
Acute Care Facilities
Other Providers Treating this Disease
Medications Treating This Disease





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