Gout (Uric Acid Joint Inflammation)
Description
Occurs when there is an imbalance between the production and excretion of uric acid. Uric acid crystals accumulate in the joints leading to acute inflammation. The attacks are usually recurrent and most commonly affect the elbow, knee, hand, foot, ankle, arm, shoulder and especially the base of the big toe. The pain can be severe preventing increasing with even the slightest touch of the affected joint.
Symptoms
Pain, swelling, redness, and increased warmth of the affected joint.
Tests
A history and physical exam will be performed. The diagnosis is made by obtaining joint fluid using a needle (arthrocentesis) and examining the fluid for uric acid crystals.
- CBC
- X-Ray
Treatment
Treatment includes: rest, nonsteroidal anti-inflammatory medications/NSAIDs (indomethacin/Indocin, ibuprofen/Motrin), colchicine, pain medications such as acetaminophen (Tylenol), and steroids. The following medications and behavioral modifications reduce the number of attacks: probenecid (Benuryl), allopurinol (Zyloprim), cessation of alcohol use, decrease the consumption of red meat and seafood.
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Is gout inherited? Three in my husband's family has gout, but none in my own. Anyone know?