Asthma

Description
An inflammatory disease of the lungs characterized by reversible airway obstruction. The tubes that carry air in the lungs are called bronchi and bronchioles. In asthma these tubes become narrowed because of abnormal muscular contraction of the tubes and from inflammation. The mucous lining of these tubes become irritated and secrete mucous and white blood cells into the airways making the narrowing worse. In some patients this narrowing occurs in response to an irritant such as cold air, dust, pollen, exercise, or tobacco smoke. The severity of symptoms vary greatly amongst patients ranging from a mild irritant to life threatening collapse.

Symptoms
Shortness of breath, wheezing, cough, low oxygen, fainting, death.

Tests
A history and physical exam will be performed. Peak expiratory flow rate will be taken to measure the lungs function and effects of treatment. A chest X-ray will be taken if infection is suspected.
- X-Ray
Treatment
Beta-agonist bronchodilators (Albuterol, levalbuterol, metaproterenol) are usually given by meter dose inhaler or nebulizer. Steroids are administered intravenously, orally or by inhalation. Parasypathetic agents such as Atrovent (ipratropium) are also used frequently. Combination medications containing a bronchodilator and steroid are also available. In severe cases positive airway pressure breathing device (BiPAP), heliox (mixture of helium and oxygen), and/or mechanical ventilation (breathing tube place in trachea) may be needed. For additional information contact the National Heart, Lung and Blood Institute Health Information Center at: http://www.nhlbi.nih.gov or call (301)592-8573 Asthma and Allergy Foundation of America: (800) 727-8562 American Lung Association: (800)586-4872 National Jewish Medical and Research Center: (800)222-5864


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