Acetaminophen (Tylenol) Poisoning

Description
Acetaminophen is primarily metabolized by the liver. Too much acetaminophen (Tylenol) can overwhelm the liver, thereby producing toxic substances that can destroy the liver, resulting in death.

Symptoms
Nausea, vomiting, fainting, yellowing skin, confusion, weakness, death.

Tests
A history and physical exam will be performed. An acetaminophen (Tylenol) level is measured as well as liver function tests.
Standard Workup
- CBC
- Chem 12
- BHCG
- Troponin
- CT Scan
- X-Ray
Treatment
The antidote, mucomyst (n-acetylcysteine) is given orally or intravenously. Mucomyst helps the body neutralize toxic metabolites. For more information and help call your local poison center at 1-800-222-1222.

Research
Severe acetaminophen poisoning treated with a fractionated plasma separation and absorption system: A case report.
Provided by: PubMed
Dental pain as a risk factor for accidental acetaminophen overdose: a case-control study.
Provided by: PubMed

News
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